Zonisamide

(zoe-NISIS-ah-MIDE)

Zonegran

Capsules

100 mg

Class: Anticonvulsant, Sulfonamide

Action Unknown; however, may produce anticonvulsant effects through action at sodium and calcium channels.
Indications Adjunctive therapy in the treatment of partial seizures in adult epileptic patients.
Contraindications Hypersensitivity to sulfonamides or zonisamide.


[ Read the rest ... ]

zonisamide side effects   zonisamide dosage   zonisamide Action   zonisamide Precautions   partial seizures   calcium channels   zonisamide   zoe   sodium

Zolpidem Tartrate

(ZOLE-pih-dem)

Ambien

Class: Sedative and hypnotic

Action Mechanism is unknown but may involve subunit modulation of the aminobutyrate activase (GABA) receptor chloride channel macromolecular complex.
Indications Short-term treatment of insomnia.
Contraindications Standard considerations.


[ Read the rest ... ]

chloride channel   action mechanism   zole   treatment of insomnia   zolpidem

Zolmitriptan

(ZOLE-mih-TRIP-tan)

Zomig

Tablets: 2.5 mg, Tablets: 5 mg

Class: Analgesic, Migraine

Action Selective agonist for the vascular serotonin (5–HT) receptor subtype, causing vasoconstriction of cranial arteries and inhibition of pro-inflammatory neuropeptide release.
Indications Short-term treatment of migraine attacks with/without aura.
Contraindications Ischemic heart disease or in patients with Prinzmetal’s angina; symptoms consistent with possible ischemic heart disease; uncontrolled hypertension; symptomatic Wolff-Parkinson-White syndrome; use within 24 hr of treatment with another 5–HT agonist or an ergotamine-containing or ergot-like medication; concurrent administration of, or within 2 wks of discontinuation of, a MAO inhibitor, management of hemiplegic or basilar migraines.


[ Read the rest ... ]

basilar migraines   wolff parkinson white syndrome   wolff parkinson white   angina symptoms   receptor subtype

Zoledronic Acid

zoledron

(zoe-leh-DROE-nik acid)

Zometa

Reconstituted Solution

4 mg per vial

Class: Bisphosphonate

Action Inhibition of bone resorption. 
Indications Treatment of hypercalcemia of malignancy; treatment of patients with multiple myeloma and bone metastases from solid tumors in conjunction with standard antineoplastic therapy. 
Contraindications Zoledronic acid or other bisphosphonates, or any excipients in the formulation. 


[ Read the rest ... ]

hypercalcemia of malignancy   zoledronic acid   bone metastases   multiple myeloma   bone resorption

Ziprasidone

(zi-PRAY-si-done)

Geodon

Tablets: 20 mg (as HCl), 40 mg (as HCl), 60 mg (as HCl), 80 mg (as HCl)

Injection: 20 mg/mL (as mesylate)

Class: Antipsychotic/Benzisoxazole

Action Antipsychotic activity, apparently because of dopamine and serotonin receptor antagonism.
Indications Treatment of schizophrenia; treatment of acute agitation in schizophrenic patients (injection only).
Contraindications Drugs known to prolong the QT interval (eg, quinidine, pimozide, sotalol); patients with a history of QT prolongation; recent acute MI; uncompensated heart failure.


[ Read the rest ... ]

acute agitation   schizophrenia treatment   qt interval   treatment of schizophrenia   ziprasidone